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Skincare — Ingredients

Niacinamide serum: what it does and how to use it.

Niacinamide serum (vitamin B3) calms redness, controls oil, refines the look of pores and fades marks. It suits almost every skin type and works morning and night.

6 minute read

Written and reviewed by Beauty World Editorial · Last reviewed October 2026

Clear niacinamide serum dropper bottle on pink stone
One of the gentlest, most versatile actives.
Niacinamide serum pairing guide: salicylic acid, hyaluronic acid and retinol

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What can you actually mix with niacinamide?

Niacinamide pairs well with salicylic acid for pores, hyaluronic acid for hydration and retinol for calmer anti-ageing.

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01

Basics

What does niacinamide serum do?

Controls oil

Helps balance sebum, so oily and combination skin looks less shiny.

Refines pores

Less oil and better barrier function make pores look smaller.

Fades marks

Reduces the transfer of pigment, helping post-spot marks and uneven tone.

Strengthens the barrier

Boosts ceramides, so skin loses less water and gets less irritated.

02

How to

How to use niacinamide serum

1. After cleansing

Apply 2–3 drops to dry skin, morning, evening or both.

2. Before moisturiser

Follow with moisturiser, then SPF 30+ in the morning.

3. Start at 5%

5% is effective for most people; 10% can tingle on sensitive skin.

4. Give it time

Expect oil and redness changes in 2–4 weeks, marks in 8–12 weeks.

03

Who it suits

Niacinamide serum for your skin type

Oily and acne-prone

Look for 5–10% with zinc for extra oil control.

Dry

Choose a formula with hyaluronic acid or glycerin.

Sensitive and rosacea-prone

Use 2–5% and patch test first.

UK pharmacy shelves

Boots and Superdrug stock niacinamide serums at every budget — check the percentage on the label rather than the price.

Common questions

Can I use niacinamide serum every day?

Yes. Most people can use it once or twice a day.

Can I use niacinamide with vitamin C?

Yes. The old warning is outdated; modern formulas work well together. Use them at different times if your skin tingles.

Can I use niacinamide with retinol?

Yes — niacinamide can make retinol feel less irritating.

Why is niacinamide breaking me out?

High strengths (10%+) or a new formula can irritate. Drop to 5% or try a different product.